Urinary Glucocorticoid Excretion

Urinary glucocorticoid excretion.

In recent years two comparatively simple methods have been described for the assessment of urinary glucocorticoid excretion. Reddy, Jenkins, and Thorn in 1952 gave details of a method for estimating urinary " 17-hydroxycorticoids." This involved extraction of the urinary glucocorticoids (cortisone and hydrocortisone) and their metabolites with n-butyl alcohol and the use of the Porter-Silber co...

Acute glucocorticoid treatment increases urinary biotin excretion and serum biotin.

Previous studies have demonstrated that glucocorticoids alter biotin metabolism. To extend these studies, the effect of dexamethasone on biotin pools was analyzed in rats consuming a purified diet containing a more physiological level of dietary biotin intake (0.06 mg/kg). Acute (5 h) dexamethasone administration (0.5 mg/kg) elicited elevated urinary glucose output as well as elevated urinary b...

Urinary growth hormone excretion.

Urinary methylmalonic acid excretion.

Urinary prostaglandin E2 and kallikrein excretion in glucocorticoid hypertension in rats.

1. Oral administration of dexamethasone (about 2.5 X 10(-7) mol/day) caused hypertension in rats. The blood pressure rose from 108 +/- 6 (mean +/- SD) to 156 +/- 17 mmHg on the seventh day. The urine volume and urinary excretion of sodium were increased. The plasma renin activity and plasma aldosterone were unchanged. However, the urinary excretions of prostaglandin E2 (UPGE2V) and kallikrein (...